Manhattan Gastroenterology
  • MIDTOWN 51 EAST 25TH, 4 FL New York, NY, 10010
  • UPPER EAST SIDE 983 PARK AVE, STE 1D New York, NY, 10028
  • UNION SQUARE 55 W. 17TH ST STE 102 New York, NY, 10011
Updated on Jun 8, 2020 by Dr. Shawn Khodadadian (Gastroenterologist) of Manhattan Gastroenterollogy

Upper endoscopy is the gold standard for evaluation of possible peptic ulcers as it allows for full visualization and an accurate diagnosis.

Peptic ulcers are breaks in the lining of the parts of the upper gut that are exposed to stomach acid. Peptic ulcers occur in the stomach (gastric ulcer) or the first part of the small intestine (duodenal ulcer), and in the oesophagus (gullet).  About 10% of people in the developed world will have an ulcer at some time in their life.  Peptic ulcer disease should always be evaluated with a thorough consultation and examination by a gastroenterologist for an accurate diagnosis and treatment plan as it may be a symptom of a serious illness or condition that needs immediate attention.

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Higher risk groups for peptic ulcers include the following:

  • Cigarette smoker
  • Family history of ulcers
  • Habitual consumer of alcohol
  • Regular user of non-steroidal, anti-inflammatory drugs (NSAIDs) such as aspirin or ibuprofen

Symptoms of Peptic Ulcer Disease

Peptic ulcer disease should always be evaluated with a thorough consultation and examination by a gastroenterologist for an accurate diagnosis and treatment plan

Ulcers sometimes don’t show any symptoms, especially if the sores are small enough, but what makes you aware of an ulcer is usually a sensation of pain. Typically, you’ll feel this pain in your abdomen.  The pain may vary over time depending on many factors. In addition to the pain associated with peptic ulcer disease, you may suffer nausea or vomiting, including vomiting blood. You also may see blood in your stool. Bloating and heartburn can also be  symptoms of an ulcer along with many other symptoms.   These are serious symptoms that need immediate attention by a gastroenterologist for an accurate diagnosis and treatment plan to exclude serious medical condition or one that requires immediate treatment.   Upper endoscopy is the gold standard for full visualization and an accurate diagnosis.

Causes of Peptic Ulcer Disease

stomach diseases

When stomach acid comes in contact with an ulcer or open sore in or around your stomach, it can cause pain. But what causes an ulcer to form in the first place? First of all, stress and diet do not cause peptic ulcer disease. An ulcer develops when either the amount of acid in your stomach increases or the amount of protective mucus decreases. One likely cause is the bacteria in the mucus, specifically the Helicobacter pylori (H. pylori) variety. H. pylori is a common infection of the stomach wall that can cause inflammation that leads to an ulcer. H. Pylori can be treated with antibiotics. The regular use of certain medications, such as NSAIDs and osteoporosis medicines is also a common cause of peptic ulcer disease. Cancer or malignancy can also be a cause of ulcers that needs to be excluded along with many other causes that should be diagnosed by an experienced gastroenterologist.

Diagnosing Peptic Ulcer Disease

Peptic ulcers

When you come in to see one of our NYC gastroenterologists, they will perform a thorough history and physical exam.  If they suspect peptic ulcer disease, but find you don’t take any of the medicines known to cause the disease, they may confirm the presence of H. pylori through a blood, stool or breath test.  An upper endoscopy is the gold standard for diagnosis and evaluation.  This exam will allow the doctor to visually confirm the existence of an ulcer and even take a biopsy sample to check for H. pylori.  Your gastroenterologist will assess the situation and decide on the correct plan for arriving at a diagnosis and further treatment regimen based on their findings.

Peptic Ulcer Treatments

Your gastroenterologist will advice you on a treatment plan after a diagnosis is made.  Limiting alcohol, avoiding smoking cigarettes and avoiding NSAIDS may be important measures. Diagnosing and treatment of h. pylori is important as well as acid suppressants to heal the ulceration may be recommended.  Upper endoscopy is important to guide our diagnosis and treatment to rule out more serious causes of ulcers and your symptoms in conjunction with biopsies that can be performed at the time of the exam.  There are many other causes of ulcers like Crohn’s disease m Zollinger-Ellison syndrome  or possible cancer which needs further workup by your gastroenterologist with a complete treatment plan.

Important Reminder: This information is only intended to provide guidance, not definitive medical advice. Please consult a GI doctor about your specific peptic ulcer condition. Only trained, experienced GI doctors like our doctors can determine an accurate diagnosis and proper treatment for your peptic ulcers.

As best in class NYC gastroenterologists, our doctors provide highly personalized and comprehensive care. For more information about peptic ulcers treatments or to schedule a consultation with one of our gastroenterologists (GI doctors), please contact our Union Square/Chelsea, Midtown or Upper East Side NYC offices.

Dr. Shawn Khodadadian has either authored or reviewed and approved this content.
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Manhattan Gastroenterology Locations: Manhattan Gastroenterology (Upper East Side) 983 Park Ave Ste 1D, NY 10028
(212) 427-8761
Manhattan Gastroenterology (Midtown) 51 East 25th Street Ste 407, NY 10010
(212) 533-2400
Manhattan Gastroenterology (Union Square) 55 W 17th St Ste 102, NY 10011
(212) 378-9983


The information on this website is to provide general information. The information on this website does NOT reflect definitive medical advice and self diagnoses should not be made based on information obtained online. It is important to consult a best in class gastroenterologist for a consultation and examination regarding ANY and ALL symptoms or signs including abdominal pain, hemorrhoids or anal / rectal bleeding as it may a sign of a serious illness or condition. An accurate diagnosis and treatment plan should only be made by your physician in order to exclude a serious condition.