Manhattan Gastroenterology
  • MIDTOWN 51 EAST 25TH, 4 FL New York, NY, 10010
  • UPPER EAST SIDE 983 PARK AVE, STE 1D New York, NY, 10028
  • UNION SQUARE 55 W. 17TH ST STE 102 New York, NY, 10011
Updated on Aug 4, 2021 by Dr. Shawn Khodadadian (Gastroenterologist) of Manhattan Gastroenterology

Celiac disease is an immune reaction to eating gluten, a protein found in wheat, barley, and rye that causes inflammation and damages the lining of your small intestine.

Celiac disease is a medical condition diagnosed by the NYC gastroenterologist that damages the lining of your small intestine. If you have celiac disease, eating gluten — a protein found in wheat, oats, rye, and barley — triggers an immune response that irritates your small intestine . Over time, the irritation causes inflammation. As a result, your body can’t absorb certain nutrients.  Celiac disease is very different and much more serious than what is called gluten intolerance. Gluten intolerance is when there is an adverse reaction  to gluten and causes symptoms, but it does not cause damage to the intestines.  This is an important distinction that your doctor should help you make with an accurate diagnosis.

Celiac disease

Celiac disease can cause bloating, weight loss, and diarrhea. Although many conditions can cause this. It can lead to malnourishment of your brain, nervous system, skeleton, and vital organs. Many of those affected by the celiac disease don’t even know it. Often, they attribute the symptoms to other causes. Sometimes, their doctors don’t consider a celiac disease. Our doctors are top NYC GI doctors (gastroenterologists), and  they consider every possibility when weighing the evidence. If celiac disease is suspected, you should always be evaluated with a thorough consultation and examination by a physician for an accurate diagnosis and treatment plan and to exclude a serious illness or condition.

★ ★ ★ ★ ★My experience with Dr. Tsynman was fantastic. I didn’t have to wait long to see him, and he showed real concern. He’s very sweet. He asked all the necessary questions and then listened to what I had to say about all of my symptoms. For once, I feel like someone is finally paying attention to my lower GI issues, and, God willing, I’ll finally have some answers.

How common is Celiac Disease?

Nearly 1 out of every 133 Americans suffer from Celiac Disease, according to a new study by the University of Maryland Center for Celiac Research in Baltimore. The research indicates that Celiac Disease is twice as common as Crohn’s disease, ulcerative colitis, and cystic fibrosis combined.

Symptoms of Celiac Disease


Celiac disease affects people differently. Although the most common symptoms are unexplained weight loss and diarrhea, other symptoms can include:

Causes of Celiac Disease

Celiac Disease

No one knows what causes celiac disease, including gastroenterologists. It may be partially genetic, but that doesn’t make a definitive case. When the disease is active, your immune system reacts to the gluten and attacks the lining of your small intestine. This action damages the villi or hairs on the inside of your small intestine. They flatten or dissolve, making it harder, if not impossible, to absorb the nutrients from the food you eat.  Because the symptoms of celiac disease can resemble the symptoms of other conditions, like Crohn’s disease or irritable bowel syndrome, our doctors will give you a physical exam and ask questions about your medical history. They’ll likely order a blood test as well, especially once he suspects celiac disease. Other tests may be needed to confirm the disease, including an upper endoscopy and a biopsy of your small intestine.

Treating Celiac Disease

Since the celiac disease has no cure, the only effective treatment is to practice a strict gluten-free diet. Eliminating all forms of gluten from your diet can help manage your symptoms and promote healing in your small intestine. Even trace amounts of gluten or an occasional “indulging” can cause damage. “Gluten-free” means to be entirely off of it, and we are happy to offer you nutritional counseling in this area. In addition to changing your diet, our doctors may recommend that you take supplements. You will need to discuss this with your gastroenterologist.

Important Reminder: This information is only intended to provide guidance, not definitive medical advice. Please consult a GI doctor about your specific condition. Only trained, experienced gastroenterologists like our doctors can determine an accurate diagnosis and proper treatment.

As best in class NYC gastroenterologists, our doctors provide highly personalized and comprehensive care. For more information about celiac disease or to schedule a consultation with one of our GI doctors, please contact our Union Square/Chelsea, Midtown, or Upper East Side NYC offices.

Dr. Shawn Khodadadian has either authored or reviewed and approved this content. Manhattan Gastroenterology Locations: Manhattan Gastroenterology (Upper East Side) 983 Park Ave Ste 1D, NY 10028
(212) 427-8761
Manhattan Gastroenterology (Midtown) 51 East 25th Street Ste 407, NY 10010
(212) 533-2400
Manhattan Gastroenterology (Union Square) 55 W 17th St Ste 102, NY 10011
(212) 378-9983


The information on this website is to provide general information. The information on this website does NOT reflect definitive medical advice and self diagnoses should not be made based on information obtained online. It is important to consult a best in class gastroenterologist for a consultation and examination regarding ANY and ALL symptoms or signs including abdominal pain, hemorrhoids or anal / rectal bleeding as it may a sign of a serious illness or condition. An accurate diagnosis and treatment plan should only be made by your physician in order to exclude a serious condition.